ISRAEL INNOVATION PROJECT

Researchers at the Weizmann Institute of Science have discovered that the BMAL1 protein, part of the body's circadian clock, plays a key role in regulating the response to oxygen deficiency, working with the HIF-1a protein. Their study shows that this interaction varies throughout the day, with a weaker response at night, which may explain why oxygen-related diseases are more common in the early morning. Additionally, their findings link liver disease to impaired lung function, providing insights into conditions like hepatopulmonary syndrome and potential future therapies.

Researchers at Tel Aviv University, in collaboration with the University of Haifa, have identified a mutation in the SHANK3 gene linked to approximately one million autism cases worldwide, marking a significant step in understanding genetically based autism. Led by Prof. Boaz Barak, doctoral student Inbar Fischer, Prof. Ben Maoz, and Prof. Shani Stern, the study highlights the potential for developing treatments to alleviate symptoms of this specific autism type.

Researchers at Tel Aviv University found that the NMDA receptor (NMDAR), known for its role in learning and memory, also stabilizes brain activity by setting neural baseline levels. Published in Neuron, the study led by Prof. Inna Slutsky used advanced techniques to show how NMDARs regulate network stability and revealed links to ketamine’s rapid antidepressant effects. These findings could lead to new treatments for depression, Alzheimer’s, and epilepsy.

A new report by Startup Nation Central highlights Israel's emergence as a global leader in artificial intelligence (AI), with AI startups comprising 30% of the country’s 7,000 startups but attracting 47% of all investment. These startups, which have nearly tripled in number since 2014, raised $3.9 billion in 2023, compared to $4.4 billion raised by non-AI companies, whose growth has been slower. Israel's AI ecosystem benefits from robust early-stage funding and the presence of global tech giants like NVIDIA, Microsoft, and Google, alongside more than 400 multinational research centers.

This year, TIME Magazine’s Best Inventions list featured 10 Israeli innovations, highlighting the nation’s influence in technology, healthcare, and sustainability. Notable contributions included Nuvo’s Invu pregnancy monitor, Aporia’s AI Guardrails, OrCam Hear’s AI hearing aid, BeeHero’s beehive monitor, and InnerPlant’s CropVoice platform.

Israeli AI startups Fermata and yieldsApp have partnered to create a farm management solution that uses real-time crop monitoring and tailored recommendations. Their system detects pests, diseases, and nutrient issues, reducing chemical use by 25% and crop losses by 30%. This eco-friendly approach aims to enhance yields amid rising climate challenges, benefiting sustainable and efficient farming.

With more couples starting families later in life, IVF has become a common solution for fertility challenges, but it carries risks like preterm births and low birthweight. To address this, Israeli company PregnanTech has developed Lioness, a non-surgical device designed to delay preterm labor. Inserted via a quick outpatient procedure, it remains stable throughout pregnancy and self-releases during active labor. Successfully tested in early trials, the device aims to improve outcomes for high-risk pregnancies, with further trials planned.

Israeli company Innoventric has secured $28.5 million in Series B funding to further develop its novel treatment for Tricuspid Regurgitation, a condition impacting cardiac blood flow. By attaching a prosthetic valve to the vena cava rather than the heart, this minimally invasive procedure avoids the need for general anesthesia and is beneficial for patients ineligible for more complicated traditional treatments. The funding will facilitate additional clinical trials and regulatory approvals.

A Tel Aviv University study reveals that the peculiar metabolic system of Oriental hornets allows them to consume high concentrations of naturally occurring alcohol without any negative effects. Unlike animals like fruit flies and tree shrews that do get adversely affected by alcohol, the hornets metabolize alcohol rapidly and show no signs of intoxication or health issues. This unique ability, possibly linked to a genetic trait, can be useful in researching alcohol metabolism in humans.

Israel’s Eco Wave Power is expanding its patented technology for generating energy from sea-waves to the east coast of Taiwan in a 100KW pilot project fully financed by I-Ke International Ocean Energy. With plans to manufacture components locally and expand capacity to 400MW over time, the project will leverage Taiwan's technological abilities and vast coastline for renewable energy, and also generate local employment opportunities.

Israeli startups are exploring unique, sustainable protein sources like jellyfish, locusts, black soldier flies, banana leaves, and microalgae protein for various food applications. These innovative companies aim to provide healthy sustainable protein alternatives, reducing ecological damage from traditional protein source production, while also addressing environmental issues like jellyfish blooms and organic farm waste.

Israeli and Japanese researchers have developed a stable peptide, D'20, that inhibits the enzyme MMP7, which promotes cancer spread, particularly in pancreatic cancer. Using cutting-edge MI-RaPID technology, they identified D'20’s high specificity in targeting MMP7 without affecting beneficial enzymes. With further research and human trials, their breakthrough discovery can offer a targeted approach to cancer treatment with fewer side effects.

A study from BGU and Sheba Medical Center found that survivors of the Oct 7 attack on the Nova music festival who had consumed alcohol and/or psychoactive drugs experienced anxiety, depression and acute stress disorders. The study also noted that of the two, alcohol consumption caused more severe peri-traumatic dissociation and post-traumatic symptoms and contributed to a delayed recovery.

Hebrew University researchers introduced a fast, versatile and non-invasive computational holography method for high-resolution imaging through complex or dense media, without needing expensive tools or prior knowledge of the target. Representing a shift from the challenging hardware-reliant approach to a computational one, their method promises broad application in medical imaging, microscopy and autonomous vehicles.

Israeli startup Inhayle has received a NASA-led grant for its patented air and surface disinfection technology that produces hydroxyl radicals, mimicking outdoor air chemistry indoors, to effectively eliminate bacteria, organic contaminants, and other pollutants. Achieving a 90% disinfection rate when tested in a hospital setting, the prototype will undergo further development for potential use in space habitats and lunar bases.

Avertto, an Israeli biotech firm, is innovating stroke intervention with AI-driven pressure sensors that monitor carotid arteries for imperceptible pulse changes that could signal a stroke. This early detection system promises to prevent over 80% of strokes and reduce related disabilities. Showing great potential in blind clinical studies, Avertto has secured $2 million in grants and is currently seeking FDA approval.

A University of Haifa study shows that 75% of genes linked to autism spectrum disorder (ASD) are also associated with schizophrenia, suggesting an increased risk for individuals with ASD. It also identifies shared underlying mechanisms between the two disorders, which could lead to more effective targeted interventions for both disorders.

Skyline Cockpit, an Israeli innovation, received the “Technology Innovation of the Year” award for its remote crane control system, which employs Artificial Intelligence and Augmented Reality to enable secure, ground-based crane operation. Greatly improving safety and efficiency, the system is already being used in major UK construction projects.

Israeli humanitarian aid and disaster relief organization, SmartAID, is providing solar-powered mobile trailers delivering electricity & communication support, along with food and medical aid to US communities in Florida and North Carolina that have been devastated by Hurricane Helene and Hurricane Milton. SmartAID’s two mobile trailers are serving as a critical communication and support resource for shelters, clinics, and first responders; atmospheric water generators as well as additional trailers are also on route.

ImmunAI, an Israeli-American biotechnology startup and developer of the pioneering AMICA™ platform, which maps immune cells using AI, has partnered with AstraZeneca in a multi-year deal. AstraZeneca will invest $18 million to utilize ImmunAI’s platform to improve drug development efficiency, gain insights in oncology research and increase the success of clinical trials.

Researchers from Technion have developed materials that significantly improve strength and longevity of the MRI signal, greatly enhancing the ability to detect metabolites—small molecules involved in metabolism and often serving as biomarkers for diseases and abnormalities. The new method, called MMV, allows better non-invasive diagnostics and could replace radiation-intensive tests, improving early disease detection and monitoring.

MOZAICO, a Technion startup, aims to enhance desalination plant efficiency with a chemical-free process that removes limescale and marine debris from cooling systems. By using electrochemical cells, the process produces pure calcium carbonate that can be sold for industrial use, reducing the need for limestone mining. Additionally, it captures atmospheric CO2, thus offering both economic and environmental advantages.

Two Israel-based startups founded by ocean enthusiasts, have created a self-stabilizing hydrofoil for beginners, and an app to streamline reservations at marinas. The pioneering hydrofoil designed by Level uses gyroscopes to maintain stability and is aimed at beginner surfers. The marina bookings app, Pick a Pier, enhances efficiency and sustainability in managing boat berths while significantly reducing paperwork for marina operators.

Israel is investing NIS 500 million ($133 million) in R&D and education to enhance its artificial intelligence capabilities over the next three years. This initiative, part of the National AI Program, aims to foster advanced research, integrate AI technologies into the defense and public services sectors and attract global talent, to maintain Israel's tech leadership amid rising global competition.

Herzliya, Israel based NeuroSense Therapeutics is developing PrimeC, a drug aimed at slowing ALS progression using a combination of existing drugs to attack multiple disease pathways simultaneously. The patented drug has shown significant improvements in patient survival and disease progression during clinical trials, and it could be available for patients within three to four years.

Five Israeli hospitals were recognized in Newsweek's list of the world's top 350 smart hospitals, with Sheba Medical Center notably ranked in 10th place. These hospitals excel in medical technologies like AI, robotics, and telemedicine, solidifying Israel's role as a hub for healthcare innovation.

Researchers at TAU developed a novel technique using super-resolution microscopy and advanced computational analysis to detect early protein aggregation, a key indicator of Parkinson's disease. This method could diagnose the disease up to 20 years before symptoms appear, enabling earlier intervention. It may also be applicable to Alzheimer's and similar disorders.

Israeli startup Zencity has been successfully using AI and big data aggregated from a variety of official and social media channels, to help local governments understand and prioritize community concerns. The service is used in over 300 cities worldwide, including New York, Chicago, LA and Tel Aviv. Zencity has raised $91 million in total funding since its launch in 2018.

Israeli startup, Brain.Q, has created a non-invasive helmet which uses low-frequency electromagnetic stimulation to enhance brain neuroplasticity and aid recovery. The startup was co-founded by physicist Yaron Segal to develop a treatment for his son’s rare neurological disorder, familial dysautonomia. Although the technology cannot currently address neurological conditions like familial dysautonomia, it has demonstrated significant benefits in trials with stroke patients and helped them regain mobility and independence, offering a promising therapeutic aid for stroke recovery.

Israeli startup H2OLL, which began as a research project at Technion, has been developing an innovative method of producing water from air, especially in arid climates. The first commercial system was recently launched in Wadi Attir in the Negev desert. Using unique adsorption technology, this system can produce water even in low atmospheric humidity, and currently has an impressive production capacity of 1000 liters of water per day. H2OLL's crowdfunding campaign has raised over 4 million shekels so far and aims to expand system capacity to 10,000 liters per day.

Salesforce, US-based Customer Relationship Management leader, acquired Israeli data backup startup Own for $1.9 billion, securing the remaining 90% ownership. Founded in 2006, Own specializes in data backup for Salesforce platforms. The deal, pending regulatory approval, is expected to close by Q4 2025, with Own's Israeli employees joining Salesforce’s development center in Israel.

With an aim to reduce plastic waste, Weizmann Institute scientists have developed a biodegradable plastic that decomposes easily with bacteria. Made from cellulose and tyrosine, this material is strong, flexible, and cost-effective, offering a variety of potential applications in the manufacturing, automotive, and cosmetic industries.

In a study spanning 15 years, Tel Aviv University researchers tracked 142 Eurasian griffon vultures, revealing that they become less social and more sedentary as they age, much like humans, the findings offer practical insights for conservation efforts, critical for protecting this endangered species in Israel.

Lensy, an Israeli startup, is developing a machine that can produce made-to-measure contact lenses using a specialized resin 3D-printing technique. This innovation aims to address issues of fit and comfort for individuals with unique eye shapes, and promises to make lenses affordable. Their desktop-sized machine, expected to be available in about four years, will allow optometrists to print custom lenses within minutes.

The study conducted by Hebrew University researchers has found that Marmosets use specific vocalizations to communicate with each other by name, making them the first non-human primates observed to do so. This behavior, seen before in dolphins and elephants, suggests that marmosets are capable of flexible and complex social communication and provides new insights into the evolutionary origins of human language and vocal learning in primates.

Tel Aviv based GaitBetter’s virtual reality fall prevention and gait rehabilitation system, which reduces fall risk by up to 80%, is now eligible for Medicare and Medicare Advantage reimbursement in 13 US states. The AI-driven, personalized system is currently installed in over 120 facilities across the US to help elderly patients and those with conditions like Parkinson’s and stroke with enhancing their cognitive and motor functions and improving overall mobility.

Israeli startup, SeismicAI uses AI to provide advanced earthquake warnings by detecting preliminary seismic waves and estimating impacts. Unlike traditional systems, SeismicAI’s platform is globally applicable, rapidly deployable, and integrates with existing sensor networks. This technology aims to enhance public safety by offering a crucial several seconds of warning before destructive waves hit.

Tel Aviv University researchers have unveiled a groundbreaking method to transform wet organic waste into biofuels, which has the potential to meet a third of Israel’s marine fuel needs. This revolutionary innovation is applicable to a wide variety of dry and wet organic waste and can help tackle Israel’s escalating waste crisis by dramatically reducing landfill use while also lowering environmental pollution and oil & gas dependency.

From Calcalist CTech - In an incredible achievement that highlights the continued excellence of Israeli academia and its global competitiveness, three Israeli universities have been ranked among the Top 100 globally in the highly regarded 2023 Shanghai Academic Ranking. The Weizmann Institute has been ranked at the 69th place, Hebrew University of Jerusalem at the 81st place. Technion is at the 85th place overall and, notably, 11th among technological universities worldwide.

A study from TAU shows that smartwatches that monitor biomarkers, combined with daily health questionnaires, can detect diseases like COVID-19 and influenza up to 73 hours before symptoms appear, prompting early intervention and treatment. The early detection can help reduce disease spread and potentially prevent future pandemics by prompting earlier behavioral changes like minimizing social contact.

Dr. Ariel Tankus of Tel Aviv University is developing a brain-computer interface that translates thoughts into speech. The technology uses hair-like electrodes implanted in the brain to detect neuron signals and feed them to a computer that uses AI algorithms to decode and “verbalize” the brain activity. This technology could enable paralyzed individuals, including those with ALS, to communicate. The groundbreaking findings were published in the journal Neurosurgery.

At Jerusalem College of Technology’s 7th annual women’s hackathon, Hack.Her.It, a team of religious women won first place for creating “TrekTag”, a radio-wave-enabled bracelet designed to communicate without reliance on cellular service. The invention aims to aid the rescue of lost or injured travelers in remote locations or in extreme weather. The competition enables participants to address real-world challenges presented by leading tech companies, thereby emphasizing the importance of empowering religious women to become workforce innovators.

CarbonBlue, an Israeli startup founded in Jan 2022, has raised over $10 million to develop its innovative method for removing carbon dioxide (CO2) from water thereby enhancing its capacity to absorb CO2 from the air and consequently reducing atmospheric CO2 concentration caused by pollution. The two-step process to separate CO2 from water is a scalable, carbon-negative solution that can be integrated into existing industrial processes and can be applied to any kind of water, even contaminated water in sewage treatment plants. Their technology aims to reduce industrial carbon footprints and has attracted significant attention for its potential environmental impact.

A 2-year study from Ben-Gurion University of the Negev shows that the use of Socially Assistive Robots (SARs) as supplementary measures in stroke rehabilitation therapy can greatly improve patient outcomes compared to using just computers or no tech at all. The SARs significantly improved both clinical measures as well as mobility, with 100% of participants showing notable recovery, suggesting a promising new approach for rehabilitation.

In a study published in Nature magazine, a team led by Tel Aviv University researchers have developed a revolutionary transparent, self-healing glass made from a unique aromatic peptide. This material forms instantly upon contact with water at room temperature. In addition to having adhesive and self-healing properties, it has extraordinary strength and is more transparent than regular glass, promising wide-ranging application in optics, communications, and biomedicine.

Edwards Lifesciences is acquiring Innovalve Bio Medical, a startup founded by heart surgeons at Sheba Medical Center, that has developed a catheter-based valve replacement system undergoing successful US clinical trials since 2021. The system offers a less invasive alternative to open-heart surgery for treating mitral valve regurgitation, the most common heart valve disease. The $300 million acquisition will provide this treatment option to millions of patients, particularly those who can’t undergo open-heart surgery.

The recently launched Israeli Quantum Computing Center (IQCC) is a pioneering facility that combines quantum and traditional supercomputers for ultra-fast processing and, notably, also provides open access to this cutting-edge hardware and software testing platform for research and development in academia and industry. Its open-architecture approach ensures constant upgradability and scalability, setting a new standard for future data centers.

A multidisciplinary team at TAU developed the Multi-Sensor Origami Platform (MSOP) using origami principles to address the challenge of placing sensors in 3D-bioprinted tissue models. Their innovative foldable structure fits around tissues, keeping sensors intact while ensuring precise placement. Successfully demonstrated with 3D printed brain tissue, the technique offers applications across a wide range of biological research fields.

Beyond Oil, an Israeli company, has created a revolutionary formula to address the dangers of the deep-rooted worldwide practice of reusing oil for frying, in both domestic and industrial practices. Reused frying oil can contain harmful substances that can lead to serious health issues both from consuming the fried foods as well as from inhaling the oil fumes. The technology involves a filtration powder that reduces harmful substances in oil and allows for safer, prolonged use, offering health and environmental benefits.

“Liquid biopsy”, a non-invasive technique that analyses bodily fluids to detect and monitor diseases, including cancer, is now advancing rapidly in Israel due to the developments in AI and machine learning. Precision oncology startup, Oncohost is combining it with AI and machine learning tools for complex data-analysis that offer insights into cancer progression, enables tailored treatments, and reduces healthcare costs. Companies like MetaSight, Senseera and Nevia Bio are developing non-invasive tests that use liquid biopsy to accurately diagnose and screen for a wide variety of diseases.

In a bid to cement its global AI leadership, Israel is planning to invest $250 million to build its first supercomputer as part of a national AI program that will span three years. With tech accounting for 20% of Israel's economy, this initiative will support over 2,200 AI startups and provide affordable AI training resources for researchers and companies.

Researchers at the Weizmann Institute have developed an MRI technique for early detection of pancreatic cancer that utilizes the tendency of tumor cells to consume more glucose than normal cells, most of which then ferments to lactate (known as Warburg Effect). Their technique works by making lactate more “visible” to MRI using a non-radioactive hydrogen isotope and then tracking it to accurately locate hidden tumors. Tested successfully in animal models, this new method has great potential for improved early pancreatic cancer detection rates in humans.

Ben-Gurion University received a $1.3 million grant from the Bill & Melinda Gates Foundation for their efforts to advance global polio eradication. Prof. Tomer Hertz and team are developing a technique called Polio Antigen Microarray (PAM) that measures immune response to polio using minimal serum or dried blood spots, allowing for safe and rapid immune response analysis. The grant will enable further development and testing of PAM on a large sample set from the Democratic Republic of Congo, with the goal of expanding polio-immunity analysis in more countries.

A Hebrew University study explored the role of attachment styles and of the partnership between therapist and patient in predicting adherence and dropout rates, and consequently the overall effectiveness of internet-based Cognitive Behavioral Therapy (CBT) in treating depression and insomnia.

An international team that included researchers from Tel Aviv University has developed a method of growing ultra-long, ultra-narrow graphene nanoribbons that exhibit semi-conducting properties, now making it possible for the electronic chips to use graphene in quantum switching devices. This breakthrough enables the fabrication of carbon-based nanoelectronic devices, with potential applications in advanced switching, spintronics, and quantum computing.

Bar-Ilan University scientists have devised an innovative method that uses worms to model human muscle diseases, offering a more scalable and versatile approach in comparison to using rodents. By transferring extracellular vesicles from patients with Duchenne muscular dystrophy to the worms, they successfully induced muscle atrophy, resembling human symptoms. This groundbreaking technique utilizes blood-derived elements, bypassing the need for genetic modifications in model organisms.

A team of international scientists, including researchers from Tel Aviv University, has discovered a black hole approximately 1,500 light years from Earth in the Milky Way galaxy with the help of the European Space Agency’s Gaia spacecraft. Dubbed Gaia BH3, it's part of a binary star system, with a star orbiting it in an 11-year cycle. This black hole is 33 times denser than the sun and three times denser than other known black holes in the galaxy.

Israeli startup Remepy is developing hybrid app + drug therapies to enhance treatment for neurodegenerative and autoimmune diseases. By combining traditional drugs with tailored digital therapeutics like cognitive-behavioral exercises and guided meditations, Remepy aims to optimize patient outcomes. The startup recently raised $10 million, bringing the total funding to $15 million.

Ben-Gurion University researchers developed a nanosized polymer to deliver chemotherapy in mice, effectively eliminating colorectal cancer liver metastases and reducing melanoma lung metastasis. This targeted method minimizes side effects by ensuring the drug specifically reaches cancer cells. Licensed to Vaxil BioTherapeutics for further clinical development, the procedure is currently being tested in large animals, with plans to begin human clinical trials as soon as possible.

Israeli researchers from the Hebrew University of Jerusalem have discovered a new insect species in exceptionally well-preserved in 99-million-year-old amber from Myanmar. Named Miropictopallium coloradmonens, this ancient bug features unique characteristics like very large eyes and vibrant coloration. This discovery provides insights into the biodiversity and ecological conditions of the Cretaceous period, enhancing our understanding of insect evolution and the historical development of ecosystems

In a deal estimated to be valued between $600 million to $700 million, Nvidia is acquiring Israeli AI workload management startup Run:ai, making this one of Nvidia’s biggest acquisitions in Israel in recent years. Founded in 2018, Run:ai simplifies AI infrastructure for businesses, helping them manage complex AI workloads and computing resources across cloud, edge, and on-premises environments, all on a unified platform.

A novel method to study the effects of psychedelics has been developed by researchers at the Weizmann Institute of Science, using zebrafish larvae. Their approach combines optical microscopy, image analysis, and AI to observe how psychedelics like psilocybin, a mushroom-derived psychedelic compound, affect brain cells and behavior. The research aims to uncover the mechanisms behind the effects of psychedelics on serotonin receptors, potentially leading to new treatments for depression, anxiety and serotonin-related disorders

Technion researchers have developed a novel ultrasound-based method for non-invasive drug delivery and tissue implantation. This technique allows for the precise delivery of cells or drugs deep within the body using sound waves emitted by an external ultrasonic transducer. Eliminating the need for risky invasive surgeries, the method has varied applications like local cell transplantation, continuous localized drug delivery, and three-dimensional bioprinting.

LETSTOP, an Israeli startup, is attempting to tackle the problem of distracted driving by incentivizing responsible behavior through its app. Using advanced tech and AI, the app tracks phone usage while driving. It then provides customized feedback to improve driving habits and rewards safe driving with credits that are redeemable for vouchers or cryptocurrency.

Israeli startup PoLoPo is employing molecular farming to cultivate egg white protein within potatoes. The gene for ovalbumin, the main protein in egg whites, is created using their new proprietary SuperAA platform and inserted into potato plants. The modified potatoes are then grown and harvested like conventional potatoes. After harvesting, the egg white protein is extracted from them and turned into a powder for commercial use in food production as a vegan-friendly protein. The company has launched pilot schemes in Israel and has plans for marketing it in the US by 2026, pending regulatory approval.

Tel Aviv University researchers have conducted a pioneering study on over 3,000 coronary heart patients post-bypass surgery, that studied the relationship between the areas where they resided and their survival rates after the operation. The study reveals that patients who resided in greener areas had an 7% lower mortality rate on average than those who lived in a relatively non-green environment. This is based on the hypothesis that living in a green environment meant better air quality and more engagement in physical activity.

Using a combination of two existing medications, Tel Aviv University researchers have developed a new strategy to combat the development of bone metastasis, a common occurrence with breast cancer. Their approach disrupts communication between cancer cells and healthy cells, thereby reducing metastases. The therapy's advantage lies in using readily available drugs. Preliminary observations have shown improved survival rates in mice, further clinical trials will determine effectiveness and safety for humans.

A research study by the University of Haifa and the Underwater Acoustic and Navigation Laboratory utilized acoustic studies of dolphin whistles and analyzed the data with deep-learning AI software, to confirm that noises from ships and other maritime traffic significantly alter the vocal behavior and communication patterns of dolphins. While the meaning of the altered communication patterns is still being studied, scientist believe it very likely relates to stress or distress responses.

Scientists at Tel Aviv University have uncovered the complex decision-making process used by bacteriophages or phages (viruses that invade bacteria). They found that after invasion, if a phage senses other phages nearby, it chooses to remain dormant; whereas if it does not sense other phages, it instead replicates and kills the host. This study has several potential applications like alleviating the effects of diseases like cholera by using phages as antibiotics alternatives to pathogenic bacteria and , with further research, gaining better insight into the behavior of human-infecting viruses.

Israeli tech startups have raised $1.6 billion in the first quarter of 2024. The number of deals increased by 35% from the previous quarter, with larger deals dominating, particularly in cyber startups, which secured $620 million in funds. This symbolizes a significant vote of confidence by investors in Israeli entrepreneurs and raises hopes of continued recovery from the fundraising drought caused by the Israel-Hamas war.

Weizmann Institute researchers were able to capitalize on a unique opportunity to observe a supernova (exploding star) in real-time and gather crucial data in the process. With initial analysis suggesting that the missing mass formed a black hole post-explosion, the study offers new insights into stellar life cycles and the formation of new cosmic entities. The study signifies a great stride in understanding the rare phenomenon of supernovae and can potentially enhance our understanding of the universe's origins.

Inspired by COVID-19 protocols, researchers have successfully used pooled saliva PCR testing to collectively screen large numbers of newborn babies for congenital cytomegalovirus (cCMV), which is a very common yet under-screened viral infection that, until now, could only be tested for using individual saliva and urine samples. The new method is faster, cost-effective, reduces false positives and enhances early detection and intervention which is crucial for managing cCMV-related complications.

A study by Bar-Ilan University researchers proposes the use of their newly developed device to detect low concentrations of pharmaceutical waste and contaminants in water, particularly the highly toxic piperidine which poses significant health risks to humans and animals. The dime-sized device uses a nano-patterned metallic surface and optical detection methods to detect piperdine even at very low concentrations. The findings of this study can revolutionize environmental waste and contaminant monitoring.

Weizmann Institute researchers have found a new yeast species that can potentially be used against a harmful yeast type called Candida albicans, which causes a deadly infection called invasive candidiasis in hospitalized and immunocompromised patients. The newly discovered species, Kazachstania weizmanni, lives harmlessly in the intestines of both mice and humans, but successfully competes with and reduces the development of Candida albicans. Showing promising results in mice, the new finding could possibly also offer a way to manage invasive candidiasis in humans.

Researchers at Bar-Ilan University, in collaboration with their Italian contemporaries at the University of Milano-Bicocca, have devised a novel method to combat Alzheimer's disease. The approach harnesses X-ray activated nanoparticles that target early-stage aggregation of A-beta, a harmful protein whose accumulation is directly linked to neurotoxicity and cognitive decline. The method has demonstrated encouraging outcomes in both neuronal cell cultures and in animal studies and presents a promising new avenue for early intervention of Alzheimer’s disease.

Israeli company Belong.Life launches BelongAI Dave - Cancer Mentor, an advanced AI app for personalized cancer support prioritizing empowerment and caregiver assistance. It provides 24/7 guidance, educational resources, and clinical trial navigation. The app utilizes a vast data repository for making accurate and personalized cancer support accessible and affordable for everyone.

Israel-based City Transformer's $17,400 foldable 2-seater electric car, the CT-2, is set to launch in July. The CT-2 is made of sustainable materials like natural fibers, recycled elements, and eco-friendly composites. Its unique design allows the wheelbase to be contracted to just 39 inches, without affecting cabin space. It boasts a top speed of 55mph, and a range of 75-112 miles.

Israeli mobility app Moovit has a new feature that aids Israeli voters in locating polling stations by inputting station numbers, offering navigation options via public transport, bicycle, or walking.

Israel's Magentiq Eye shared findings from a clinical trial of its Magentiq-Colo CADe tool which demonstrates greatly improved adenoma detection during colonoscopies, with a 99.6% sensitivity and 98% specificity. Cleared by the FDA in July 2023, the device uses AI to spot adenomas in real-time videos, aiding colorectal screening.

Israeli scientists have created sustainable aviation fuel (SAF) to address the environmental impact of aviation. CarboNGV, a collaboration between Ben-Gurion University and the Ralco Group, uses industrial waste and other materials to produce sustainable aviation fuel (SAF) via a proprietary method. The first CarobNGV demonstration plant is expected to become operational by 2025.

Research from Tel Aviv University and Sheba Medical Center suggests a positive link between exposure UV radiation and fertility in women aged 30–40. By observing seasonal AMH hormone fluctuations, it was found that older women exhibited increased fertility markers during summer while younger women showed no significant correlation. Further studies will be needed to understand the mechanism and establish safe exposure levels.

A team led by researchers from Tel Aviv University and the Volcani Institute, has developed compounds that boost the rooting of plant cuttings, a stage that is critical for the propagation of plants with desirable traits. They found that introducing a synthetic, slow-release version of the plant hormone auxin (responsible for plant rooting and other vital developmental functions) greatly improved the rooting ability of plant cuttings. This is a significant discovery that can potentially reduce costs, improve crop quality, and help develop more climate-adaptable plant varieties.

Bar-Ilan University researchers led by doctoral student Belal Abu Salha, have devised a method by which strawberries are coated with nanoparticles made of chitosan, which is an edible natural substance with antibacterial properties. This treatment effectively prolongs their shelf life by up to 15 days. This breakthrough not only benefits strawberry growers but also holds promise for enhancing food preservation industry-wide, offering eco-friendly solutions to extend the freshness of various produce.

Israel's IDE Technologies is seeking to expand its desalination and water recycling services in the Philippines, engaging in talks with local partners for potential ventures. With impending water scarcity in the region due to El Niño, IDE emphasizes water recycling and environmentally friendly solutions tailored to the Philippines' unique challenges.

OPENLANE, a major US vehicle marketplace, has integrated Israeli tech company Click-Ins' AI system to detect vehicle damage from real-time images and generate visual overlays that allow customers to quickly and accurately assess the exterior condition of used vehicles. UVeye is an Israeli AI-powered vehicle inspection system that is already in use at hundreds of US GM dealerships to improve the accuracy of vehicle inspections.

From The Times of Israel - As a potential way to combat global warming, scientists from Technion propose deploying a series of sunshades in space for reflecting sunlight away from Earth. The project, called "Cool Earth", is still in the early stages, but based on calculations it offers a promising solution to mitigate the effects of climate change.

Professor Gad Vatine from Ben-Gurion University and Dr. Avraham Ashkenazi from Tel Aviv University, have teamed up to study a rare but potentially fatal disorder in young children called Central Congenital Hypoventilation Syndrome (CCHS), which can cause a child to stop breathing while asleep. They have found that CCHS stems from a PHOX2B gene mutation that affects the Autonomic Nervous System. This finding provides insights into the disease mechanism and opens up possibilities for developing treatments to improve the quality of life for patients with CCHS.

Israeli biotechnology company Pluri Inc. unveils its breakthrough in cultured coffee bean production, aiming to transform the global coffee market. Utilizing PluriMatrix technology, the process grows coffee cells in a lab that offer the same taste and aroma as regular coffee, with added sustainability benefits that help reduce environmental impact and address challenges posed by climate change.

Israeli AI startup Storywizard.ai won the Global Edtech Startup Awards (GESA) in London. The platform enables children to create, edit, and illustrate their own bedtime stories with the help of AI. The program has also found an application in the education sector as teachers globally have adopted it craft classroom educational aids. It has already been integrated into hundreds of Israeli schools since September 2023 and in over 1,500 schools worldwide.

Tel Aviv University scientists used CRISPR genetic editing technology to grow tomato plants that need less water but still produce plenty of fruit. They targeted a gene called ROP9 to partially close the plant's pores, reducing water loss without harming growth. This breakthrough could benefit other crops as well, leading to more efficient water use in agriculture.

Israeli innovators, supported by EU funding, are aiming to produce handbags made of fish skin, for eco-friendly fashion. Their idea is to repurpose fish skin, which is typically a waste material, into leather that offers sustainability benefits. The collaboration, currently at the proof-of-concept stage, is seeking industrial adoption, emphasizing its potential for sustainability and innovation in the fashion industry.

A recent study by Ben-Gurion University researchers uncovers how anxiety and testosterone are linked at the molecular level, shedding light on potential treatments for anxiety. They found that a protein called TACR3, present in the brain, connects low testosterone levels to anxiety. Through experiments on rats, they discovered that higher testosterone levels corresponded to lower anxiety, and vice versa.

New research from Hebrew University-Hadassah Faculty of Dental Medicine shows that oscillating-rotating electric toothbrushes outperform traditional toothbrushes in reducing plaque and gingivitis in children (ages 3-10). Children using electric brushes had significantly better results in plaque and gingivitis reduction, emphasizing their oral health benefits.

Oracle CEO, Safra Catz, has confirmed plans to open a second data center in Israel, emphasizing the need for robust and secure cloud services during war. With this nine-floor secure underground facility, oracle aims to double its investment and enhance cloud services in Israel.

A groundbreaking study by Hebrew University reveals how supermassive black holes generate intense light during Tidal Disruption Events (TDEs). Through advanced simulations, researchers accurately recreated the entire TDE process, identifying a previously unknown shockwave type that powers the brightest phases of these events. The findings offer insight into black hole properties and may validate Einstein's theories in extreme gravitational conditions, shaping future astronomical exploration.

Tel Aviv based 101 Therapeutics, in partnership with Canadian-Israeli venture capital firm, AWZ has developed a new COVID treatment that could change how we fight the pandemic. It targets immune cells called macrophages, helping remove infected cells and stopping dangerous immune overreactions referred to as a “cytokine storm”. Notably, this drug is “pathogen agnostic” and as such, it is poised to be a crucial solution for addressing future pandemics and biosecurity threats.

After rigorous safety assessments, Aleph Farms, an Israeli food-tech start-up, has received regulatory approval to sell lab-grown steak in Israel, marking a significant milestone in cultivated meat technology. The process uses sample cells from a live animal that are then cultivated in a controlled environment and blended with plant proteins from soy and wheat. Aleph Farms plan to commercialize its product in the Israeli food service and retail markets soon.

A portable virtual reality system by Israeli startup XRHealth aids brain-injured patients' recovery at Sheba Medical Center. The VR system, used by occupational therapists, enhances cognitive and motor skills through interactive game-like activities. It offers an engaging and motivating approach for rehabilitation that can be utilized in hospitals or at home under remote supervision.

From Calcalist CTech - Imagindairy, a foodtech startup, has secured FDA approval for their non-GMO, cholesterol-free, and eco-friendly animal-free milk proteins produced through precision-fermentation technology.

An innovation center for climate and desert technology is opening in Be’er Sheva, Israel, and will span the Negev and Arava regions. One of nine centers, it aims to promote employment and technological advancement in the Negev, develop new companies, strengthen the high-tech sector, and integrate locals into the industry.